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A Size-Exclusion Permeability Barrier and Nucleoporins Characterize a Ciliary Pore Complex that Regulates Transport into Cilia

The cilium is a microtubule-based organelle that contains a unique complement of proteins for cell motility and signaling functions. Entry into the ciliary compartment is proposed to be regulated at the base of the cilium (1). Recent work demonstrated that components of the nuclear import machinery,...

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Detalles Bibliográficos
Autores principales: Kee, Hooi Lynn, Dishinger, John F., Blasius, T. Lynne, Liu, Chia-Jen, Margolis, Ben, Verhey, Kristen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319646/
https://www.ncbi.nlm.nih.gov/pubmed/22388888
http://dx.doi.org/10.1038/ncb2450