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The Molecular Architecture of Human Dicer

Dicer is a multi-domain enzyme that generates small RNAs for gene silencing in eukaryotes. Current understanding of Dicer structure is restricted to simple forms of the enzyme, while that of the large and complex Dicer, widespread in eukarya, is unknown. Here, we describe a novel domain localization...

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Detalles Bibliográficos
Autores principales: Lau, Pick-Wei, Guiley, Keelan Z., De, Nabanita, Potter, Clinton S., Carragher, Bridget, MacRae, Ian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319852/
https://www.ncbi.nlm.nih.gov/pubmed/22426548
http://dx.doi.org/10.1038/nsmb.2268