Pharmacogenomics of Human ABC Transporter ABCC11 (MRP8): Potential Risk of Breast Cancer and Chemotherapy Failure

Some genetic polymorphisms of human ABC transporter genes are reportedly related to the risk of certain diseases and patients’ responses to medication. Human ABCC11 functions as an ATP-dependent efflux pump for amphipathic anions. One non-synonymous SNP 538G>A (Gly180Arg) has been found to greatl...

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Detalles Bibliográficos
Autores principales: Toyoda, Yu, Ishikawa, Toshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers Ltd 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319924/
https://www.ncbi.nlm.nih.gov/pubmed/21182469
http://dx.doi.org/10.2174/187152010794473975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319924/
https://www.ncbi.nlm.nih.gov/pubmed/21182469
http://dx.doi.org/10.2174/187152010794473975

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