Cargando…

Pharmacogenomics of Human ABC Transporter ABCC11 (MRP8): Potential Risk of Breast Cancer and Chemotherapy Failure

Some genetic polymorphisms of human ABC transporter genes are reportedly related to the risk of certain diseases and patients’ responses to medication. Human ABCC11 functions as an ATP-dependent efflux pump for amphipathic anions. One non-synonymous SNP 538G>A (Gly180Arg) has been found to greatl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Toyoda, Yu, Ishikawa, Toshihisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers Ltd 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319924/ https://www.ncbi.nlm.nih.gov/pubmed/21182469 http://dx.doi.org/10.2174/187152010794473975

Ejemplares similares

Pharmacogenetics of human ABC transporter ABCC11: new insights into apocrine gland growth and metabolite secretion
por: Ishikawa, Toshihisa, et al.
Publicado: (2013)

Genetic variation of the ABC transporter gene ABCC1 (Multidrug resistance protein 1 – MRP1) in the Polish population
por: Słomka, Marcin, et al.
Publicado: (2015)

Clinicopathological Impact of ABCC1/MRP1 and ABCC4/MRP4 in Epithelial Ovarian Carcinoma
por: Bagnoli, Marina, et al.
Publicado: (2013)

ABCC11/MRP8 Expression in the Gastrointestinal Tract and a Novel Role for Pepsinogen Secretion
por: Matsumoto, Hirofumi, et al.
Publicado: (2014)

MRP8/ABCC11 Expression Is Regulated by Dexamethasone in Breast Cancer Cells and Is Associated to Progesterone Receptor Status in Breast Tumors
por: Honorat, Mylène, et al.
Publicado: (2011)

ABCC4/MRP4: a MYCN-regulated transporter and potential therapeutic target in neuroblastoma
por: Huynh, Tony, et al.
Publicado: (2012)

Genome-wide identification and expression characterization of ABCC-MRP transporters in hexaploid wheat
por: Bhati, Kaushal K., et al.
Publicado: (2015)

Overexpression of MRP4 (ABCC4) and MRP5 (ABCC5) confer resistance to the nucleoside analogs cytarabine and troxacitabine, but not gemcitabine
por: Adema, Auke D, et al.
Publicado: (2014)

Diagnosis of Human Axillary Osmidrosis by Genotyping of the Human ABCC11 Gene: Clinical Practice and Basic Scientific Evidence
por: Toyoda, Yu, et al.
Publicado: (2016)

Regulation of the Axillary Osmidrosis-Associated ABCC11 Protein Stability by N-Linked Glycosylation: Effect of Glucose Condition
por: Toyoda, Yu, et al.
Publicado: (2016)

Clinical and Molecular Evidence of ABCC11 Protein Expression in Axillary Apocrine Glands of Patients with Axillary Osmidrosis
por: Toyoda, Yu, et al.
Publicado: (2017)

Multidrug transporter MRP4/ABCC4 as a key determinant of pancreatic cancer aggressiveness
por: Sahores, A., et al.
Publicado: (2020)

Wnt‐β‐catenin signaling regulates ABCC3 (MRP3) transporter expression in colorectal cancer
por: Kobayashi, Minoru, et al.
Publicado: (2016)

Reversal of MRP7 (ABCC10)-Mediated Multidrug Resistance by Tariquidar
por: Sun, Yue-Li, et al.
Publicado: (2013)

Functional Expression of Multidrug Resistance Protein 4 MRP4/ABCC4
por: Hardy, David, et al.
Publicado: (2019)

Structural basis for the channel function of a degraded ABC transporter, CFTR (ABCC7)
por: Bai, Yonghong, et al.
Publicado: (2011)

Specific inhibition of the transporter MRP4/ABCC4 affects multiple signaling pathways and thrombus formation in human platelets
por: Wolf, Robert, et al.
Publicado: (2022)

Calcitriol and Calcipotriol Modulate Transport Activity of ABC Transporters and Exhibit Selective Cytotoxicity in MRP1-overexpressing Cells
por: Tan, Kee W., et al.
Publicado: (2018)

In Vitro Assessment of the Effect of Antiepileptic Drugs on Expression and Function of ABC Transporters and Their Interactions with ABCC2
por: Grewal, Gurpreet Kaur, et al.
Publicado: (2017)

ABCC Transporter Gene MoABC-R1 Is Associated with Pyraclostrobin Tolerance in Magnaporthe oryzae
por: Hu, Pei, et al.
Publicado: (2023)

Collagen/β1 integrin signaling up-regulates the ABCC1/MRP-1 transporter in an ERK/MAPK-dependent manner
por: El Azreq, Mohammed-Amine, et al.
Publicado: (2012)

The Role of Eukaryotic and Prokaryotic ABC Transporter Family in Failure of Chemotherapy
por: El-Awady, Raafat, et al.
Publicado: (2017)

Amplification and expression of the ABC transporters ARA and MRP in a series of multidrug-resistant leukaemia cell sublines.
por: O'Neill, G. M., et al.
Publicado: (1998)

Localization of the ATP-binding cassette (ABC) transport proteins PfMRP1, PfMRP2, and PfMDR5 at the Plasmodium falciparum plasma membrane
por: Kavishe, Reginald A, et al.
Publicado: (2009)

Urinary Elimination of Coproporphyrins Is Dependent on ABCC2 Polymorphisms and Represents a Potential Biomarker of MRP2 Activity in Humans
por: Benz-de Bretagne, Isabelle, et al.
Publicado: (2011)

Abcc6 deficiency in mice leads to altered ABC transporter gene expression in metabolic active tissues
por: Ibold, Bettina, et al.
Publicado: (2019)

Overexpression of MRP1/ABCC1, Survivin and BCRP/ABCC2 Predicts the Resistance of Diffuse Large B-Cell Lymphoma to R-CHOP Treatment
por: Mandić, Danijela, et al.
Publicado: (2023)

A Human ABC Transporter ABCC4 Gene SNP (rs11568658, 559 G > T, G187W) Reduces ABCC4-Dependent Drug Resistance
por: Tsukamoto, Megumi, et al.
Publicado: (2019)

Genistein and Glyceollin Effects on ABCC2 (MRP2) and ABCG2 (BCRP) in Caco-2 Cells
por: Schexnayder, Chandler, et al.
Publicado: (2015)

PD173074, a selective FGFR inhibitor, reverses MRP7 (ABCC10)-mediated MDR
por: Anreddy, Nagaraju, et al.
Publicado: (2014)

Extracellular mutation induces an allosteric effect across the membrane and hampers the activity of MRP1 (ABCC1)
por: Bin Kanner, Yuval, et al.
Publicado: (2021)

Role of ABC transporters in cancer chemotherapy
por: Sun, Yue-Li, et al.
Publicado: (2012)

Involvement of human and canine MRP1 and MRP4 in benzylpenicillin transport
por: Zhao, Xiaofen, et al.
Publicado: (2019)

The diagnostic and prognostic value of MRP8/MRP14 in intrahepatic cholangiocarcinoma
por: Jin, Guang-Zhi, et al.
Publicado: (2015)

Imatinib and Nilotinib Reverse Multidrug Resistance in Cancer Cells by Inhibiting the Efflux Activity of the MRP7 (ABCC10)
por: Shen, Tong, et al.
Publicado: (2009)

Synthesis and Biological Evaluation of Pentacyclic Strychnos Alkaloids as Selective Modulators of the ABCC10 (MRP7) Efflux Pump
por: Teijaro, Christiana N., et al.
Publicado: (2014)

Stabilization of Human Multidrug Resistance Protein 4 (MRP4/ABCC4) Using Novel Solubilization Agents
por: Hardy, David, et al.
Publicado: (2019)

Cadmium-inducible expression of the ABC-type transporter AtABCC3 increases phytochelatin-mediated cadmium tolerance in Arabidopsis
por: Brunetti, Patrizia, et al.
Publicado: (2015)

Soy Isoflavone Genistein Inhibits an Axillary Osmidrosis Risk Factor ABCC11: In Vitro Screening and Fractional Approach for ABCC11-Inhibitory Activities in Plant Extracts and Dietary Flavonoids
por: Saito, Hiroki, et al.
Publicado: (2020)

Metabolic Interactions of Purine Derivatives with Human ABC Transporter ABCG2: Genetic Testing to Assess Gout Risk
por: Ishikawa, Toshihisa, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_74ssr2al9g1rib1vfri8so17b9