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Novel model of neuronal bioenergetics: postsynaptic utilization of glucose but not lactate correlates positively with Ca(2+) signalling in cultured mouse glutamatergic neurons

We have previously investigated the relative roles of extracellular glucose and lactate as fuels for glutamatergic neurons during synaptic activity. The conclusion from these studies was that cultured glutamatergic neurons utilize glucose rather than lactate during NMDA (N-methyl-d-aspartate)-induce...

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Detalles Bibliográficos
Autores principales: Bak, Lasse K., Obel, Linea F., Walls, Anne B., Schousboe, Arne, Faek, Sevan A.A., Jajo, Farah S., Waagepetersen, Helle S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320216/
https://www.ncbi.nlm.nih.gov/pubmed/22385215
http://dx.doi.org/10.1042/AN20120004