Effects of genetic variation in H3K79 methylation regulatory genes on clinical blood pressure and blood pressure response to hydrochlorothiazide

BACKGROUND: Nearly one-third of the United States adult population suffers from hypertension. Hydrochlorothiazide (HCTZ), one of the most commonly used medications to treat hypertension, has variable efficacy. The renal epithelial sodium channel (ENaC) provides a mechanism for fine-tuning sodium exc...

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Detalles Bibliográficos
Autores principales: Duarte, Julio D, Zineh, Issam, Burkley, Ben, Gong, Yan, Langaee, Taimour Y, Turner, Stephen T, Chapman, Arlene B, Boerwinkle, Eric, Gums, John G, Cooper-DeHoff, Rhonda M, Beitelshees, Amber L, Bailey, Kent R, Fillingim, Roger B, Kone, Bruce C, Johnson, Julie A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320544/
https://www.ncbi.nlm.nih.gov/pubmed/22440088
http://dx.doi.org/10.1186/1479-5876-10-56

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320544/
https://www.ncbi.nlm.nih.gov/pubmed/22440088
http://dx.doi.org/10.1186/1479-5876-10-56

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