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Mutations of complement lectin pathway genes MBL2 and MASP2 associated with placental malaria

BACKGROUND: Innate immunity plays a crucial role in the host defense against malaria including Plasmodium falciparum malaria in pregnancy, but the roles of the various underlying genes and mechanisms predisposing to the disease are poorly understood. METHODS: 98 single-nucletoide polymorphisms were...

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Detalles Bibliográficos
Autores principales: Holmberg, Ville, Onkamo, Päivi, Lahtela, Elisa, Lahermo, Päivi, Bedu-Addo, George, Mockenhaupt, Frank P, Meri, Seppo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320545/
https://www.ncbi.nlm.nih.gov/pubmed/22380611
http://dx.doi.org/10.1186/1475-2875-11-61