Genomic and functional analysis identifies CRKL as an oncogene amplified in lung cancer

DNA amplifications, leading to the overexpression of oncogenes, are a cardinal feature of lung cancer and directly contribute to its pathogenesis. To uncover novel such alterations, we performed an array-based comparative genomic hybridization survey of 128 non-small cell lung cancer cell lines and...

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Detalles Bibliográficos
Autores principales: Kim, Young H., Kwei, Kevin A., Girard, Luc, Salari, Keyan, Kao, Jessica, Pacyna-Gengelbach, Manuela, Wang, Pei, Hernandez-Boussard, Tina, Gazdar, Adi F., Petersen, Iver, Minna, John D., Pollack, Jonathan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320568/
https://www.ncbi.nlm.nih.gov/pubmed/19966867
http://dx.doi.org/10.1038/onc.2009.437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320568/
https://www.ncbi.nlm.nih.gov/pubmed/19966867
http://dx.doi.org/10.1038/onc.2009.437

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