Parameters in Dynamic Models of Complex Traits are Containers of Missing Heritability

Polymorphisms identified in genome-wide association studies of human traits rarely explain more than a small proportion of the heritable variation, and improving this situation within the current paradigm appears daunting. Given a well-validated dynamic model of a complex physiological trait, a subs...

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Detalles Bibliográficos
Autores principales: Wang, Yunpeng, Gjuvsland, Arne B., Vik, Jon Olav, Smith, Nicolas P., Hunter, Peter J., Omholt, Stig W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320574/
https://www.ncbi.nlm.nih.gov/pubmed/22496634
http://dx.doi.org/10.1371/journal.pcbi.1002459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320574/
https://www.ncbi.nlm.nih.gov/pubmed/22496634
http://dx.doi.org/10.1371/journal.pcbi.1002459

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