Cargando…

Group A Streptococcus Secreted Esterase Hydrolyzes Platelet-Activating Factor to Impede Neutrophil Recruitment and Facilitate Innate Immune Evasion

The innate immune system is the first line of host defense against invading organisms. Thus, pathogens have developed virulence mechanisms to evade the innate immune system. Here, we report a novel means for inhibition of neutrophil recruitment by Group A Streptococcus (GAS). Deletion of the secrete...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Mengyao, Zhu, Hui, Li, Jinquan, Garcia, Cristiana C., Feng, Wenchao, Kirpotina, Liliya N., Hilmer, Jonathan, Tavares, Luciana P., Layton, Arthur W., Quinn, Mark T., Bothner, Brian, Teixeira, Mauro M., Lei, Benfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320582/
https://www.ncbi.nlm.nih.gov/pubmed/22496650
http://dx.doi.org/10.1371/journal.ppat.1002624