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Regulation of Budding Yeast Mating-Type Switching Donor Preference by the FHA Domain of Fkh1

During Saccharomyces cerevisiae mating-type switching, an HO endonuclease-induced double-strand break (DSB) at MAT is repaired by recombining with one of two donors, HMLα or HMR a, located at opposite ends of chromosome III. MAT a cells preferentially recombine with HMLα; this decision depends on th...

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Detalles Bibliográficos
Autores principales: Li, Jin, Coïc, Eric, Lee, Kihoon, Lee, Cheng-Sheng, Kim, Jung-Ae, Wu, Qiuqin, Haber, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320585/
https://www.ncbi.nlm.nih.gov/pubmed/22496671
http://dx.doi.org/10.1371/journal.pgen.1002630