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Regulation of Mycobacterium tuberculosis-Dependent HIV-1 Transcription Reveals a New Role for NFAT5 in the Toll-Like Receptor Pathway

Tuberculosis (TB) disease in HIV co-infected patients contributes to increased mortality by activating innate and adaptive immune signaling cascades that stimulate HIV-1 replication, leading to an increase in viral load. Here, we demonstrate that silencing of the expression of the transcription fact...

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Detalles Bibliográficos
Autores principales: Ranjbar, Shahin, Jasenosky, Luke D., Chow, Nancy, Goldfeld, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320587/
https://www.ncbi.nlm.nih.gov/pubmed/22496647
http://dx.doi.org/10.1371/journal.ppat.1002620