Productive Hepatitis C Virus Infection of Stem Cell-Derived Hepatocytes Reveals a Critical Transition to Viral Permissiveness during Differentiation

Primary human hepatocytes isolated from patient biopsies represent the most physiologically relevant cell culture model for hepatitis C virus (HCV) infection, but these primary cells are not readily accessible, display individual variability, and are largely refractory to genetic manipulation. Hepat...

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Detalles Bibliográficos
Autores principales: Wu, Xianfang, Robotham, Jason M., Lee, Emily, Dalton, Stephen, Kneteman, Norman M., Gilbert, David M., Tang, Hengli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320597/
https://www.ncbi.nlm.nih.gov/pubmed/22496645
http://dx.doi.org/10.1371/journal.ppat.1002617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320597/
https://www.ncbi.nlm.nih.gov/pubmed/22496645
http://dx.doi.org/10.1371/journal.ppat.1002617

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