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A Genome-Wide Screen for Genetic Variants That Modify the Recruitment of REST to Its Target Genes
Increasing numbers of human diseases are being linked to genetic variants, but our understanding of the mechanistic links leading from DNA sequence to disease phenotype is limited. The majority of disease-causing nucleotide variants fall within the non-protein-coding portion of the genome, making it...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320604/ https://www.ncbi.nlm.nih.gov/pubmed/22496669 http://dx.doi.org/10.1371/journal.pgen.1002624 |