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A Genome-Wide Screen for Genetic Variants That Modify the Recruitment of REST to Its Target Genes

Increasing numbers of human diseases are being linked to genetic variants, but our understanding of the mechanistic links leading from DNA sequence to disease phenotype is limited. The majority of disease-causing nucleotide variants fall within the non-protein-coding portion of the genome, making it...

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Detalles Bibliográficos
Autores principales: Johnson, Rory, Richter, Nadine, Bogu, Gireesh K., Bhinge, Akshay, Teng, Siaw Wei, Choo, Siew Hua, Andrieux, Lise O., de Benedictis, Cinzia, Jauch, Ralf, Stanton, Lawrence W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320604/
https://www.ncbi.nlm.nih.gov/pubmed/22496669
http://dx.doi.org/10.1371/journal.pgen.1002624