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The Impact of Imputation on Meta-Analysis of Genome-Wide Association Studies
Genotype imputation is often used in the meta-analysis of genome-wide association studies (GWAS), for combining data from different studies and/or genotyping platforms, in order to improve the ability for detecting disease variants with small to moderate effects. However, how genotype imputation aff...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320624/ https://www.ncbi.nlm.nih.gov/pubmed/22496814 http://dx.doi.org/10.1371/journal.pone.0034486 |