Alignment-Free Design of Highly Discriminatory Diagnostic Primer Sets for Escherichia coli O104:H4 Outbreak Strains

BACKGROUND: An Escherichia coli O104:H4 outbreak in Germany in summer 2011 caused 53 deaths, over 4000 individual infections across Europe, and considerable economic, social and political impact. This outbreak was the first in a position to exploit rapid, benchtop high-throughput sequencing (HTS) te...

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Detalles Bibliográficos
Autores principales: Pritchard, Leighton, Holden, Nicola J., Bielaszewska, Martina, Karch, Helge, Toth, Ian K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320637/
https://www.ncbi.nlm.nih.gov/pubmed/22496820
http://dx.doi.org/10.1371/journal.pone.0034498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320637/
https://www.ncbi.nlm.nih.gov/pubmed/22496820
http://dx.doi.org/10.1371/journal.pone.0034498

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