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Repertoire Enhancement with Adoptively Transferred Female Lymphocytes Controls the Growth of Pre-Implanted Murine Prostate Cancer

BACKGROUND: In prostate cancer, genes encoding androgen-regulated, Y-chromosome-encoded, and tissue-specific antigens may all be overexpressed. In the adult male host, however, most high affinity T cells targeting these potential tumor rejection antigens will be removed during negative selection. In...

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Detalles Bibliográficos
Autores principales: Jenq, Robert R., Curran, Michael A., Goldberg, Gabrielle L., Liu, Chen, Allison, James P., van den Brink, Marcel R. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320876/
https://www.ncbi.nlm.nih.gov/pubmed/22493742
http://dx.doi.org/10.1371/journal.pone.0035222