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Performance Analysis of Orthogonal Pairs Designed for an Expanded Eukaryotic Genetic Code
BACKGROUND: The suppression of amber stop codons with non-canonical amino acids (ncAAs) is used for the site-specific introduction of many unusual functions into proteins. Specific orthogonal aminoacyl-tRNA synthetase (o-aaRS)/amber suppressor tRNA(CUA) pairs (o-pairs) for the incorporation of ncAAs...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320878/ https://www.ncbi.nlm.nih.gov/pubmed/22493661 http://dx.doi.org/10.1371/journal.pone.0031992 |