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Icariside II Induces Apoptosis in U937 Acute Myeloid Leukemia Cells: Role of Inactivation of STAT3-Related Signaling

BACKGROUND: The aim of this study is to determine anti-cancer effect of Icariside II purified from the root of Epimedium koreanum Nakai on human acute myeloid leukemia (AML) cell line U937. METHODOLOGY/PRINCIPAL FINDINGS: Icariside II blocked the growth U937 cells in a dose- and time-dependent manne...

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Detalles Bibliográficos
Autores principales: Kang, Sang-Hun, Jeong, Soo-Jin, Kim, Sun-Hee, Kim, Ji-Hyun, Jung, Ji Hoon, Koh, Wonil, Kim, Jung Hyo, Kim, Dae Keun, Chen, Chang-Yan, Kim, Sung-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320887/
https://www.ncbi.nlm.nih.gov/pubmed/22493659
http://dx.doi.org/10.1371/journal.pone.0028706