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Further in Vitro Exploration Fails to Support the Allosteric Three-site Model

Ongoing debate in the ribosome field has focused on the role of bound E-site tRNA and the Shine-Dalgarno-anti-Shine-Dalgarno (SD-aSD) interaction on A-site tRNA interactions and the fidelity of tRNA selection. Here we use an in vitro reconstituted Escherichia coli translation system to explore the r...

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Detalles Bibliográficos
Autores principales: Petropoulos, Alexandros D., Green, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320913/
https://www.ncbi.nlm.nih.gov/pubmed/22378789
http://dx.doi.org/10.1074/jbc.C111.330068