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Herpes Simplex Virus ICP27 Protein Directly Interacts with the Nuclear Pore Complex through Nup62, Inhibiting Host Nucleocytoplasmic Transport Pathways

The herpes simplex virus ICP27 protein is important for the expression and nuclear export of viral mRNAs. Although several binding sites have been mapped along the ICP27 sequence for various RNA and protein partners, including the transport receptor TAP of the host cell nuclear transport machinery,...

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Detalles Bibliográficos
Autores principales: Malik, Poonam, Tabarraei, Alijan, Kehlenbach, Ralph H., Korfali, Nadia, Iwasawa, Ryota, Graham, Sheila V., Schirmer, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3320978/
https://www.ncbi.nlm.nih.gov/pubmed/22334672
http://dx.doi.org/10.1074/jbc.M111.331777