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Growth Hormone Improves Growth Retardation Induced by Rapamycin without Blocking Its Antiproliferative and Antiangiogenic Effects on Rat Growth Plate

Rapamycin, an immunosuppressant agent used in renal transplantation with antitumoral properties, has been reported to impair longitudinal growth in young individuals. As growth hormone (GH) can be used to treat growth retardation in transplanted children, we aimed this study to find out the effect o...

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Detalles Bibliográficos
Autores principales: Álvarez-García, Óscar, García-López, Enrique, Loredo, Vanessa, Gil-Peña, Helena, Mejía-Gaviria, Natalia, Rodríguez-Suárez, Julián, Ordóñez, Flor Á., Santos, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321024/
https://www.ncbi.nlm.nih.gov/pubmed/22493717
http://dx.doi.org/10.1371/journal.pone.0034788