Cargando…
Growth Hormone Improves Growth Retardation Induced by Rapamycin without Blocking Its Antiproliferative and Antiangiogenic Effects on Rat Growth Plate
Rapamycin, an immunosuppressant agent used in renal transplantation with antitumoral properties, has been reported to impair longitudinal growth in young individuals. As growth hormone (GH) can be used to treat growth retardation in transplanted children, we aimed this study to find out the effect o...
Autores principales: | Álvarez-García, Óscar, García-López, Enrique, Loredo, Vanessa, Gil-Peña, Helena, Mejía-Gaviria, Natalia, Rodríguez-Suárez, Julián, Ordóñez, Flor Á., Santos, Fernando |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321024/ https://www.ncbi.nlm.nih.gov/pubmed/22493717 http://dx.doi.org/10.1371/journal.pone.0034788 |
Ejemplares similares
-
Rapamycin retards growth and causes marked alterations in
the growth plate of young rats
por: Alvarez-Garcia, Oscar, et al.
Publicado: (2007) -
Antiangiogenic Therapy Using Sunitinib Combined with Rapamycin Retards Tumor Growth But Promotes Metastasis()
por: Yin, Tao, et al.
Publicado: (2014) -
Novel compounds with antiangiogenic and antiproliferative potency for growth control of testicular germ cell tumours
por: Nitzsche, B, et al.
Publicado: (2010) -
Retarded Growth
Publicado: (1883) -
Intrauterine growth retardation promotes fetal intestinal autophagy in rats via the mechanistic target of rapamycin pathway
por: WANG, Chao, et al.
Publicado: (2017)