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Reactive Oxygen Species Facilitate Translocation of Hormone Sensitive Lipase to the Lipid Droplet During Lipolysis in Human Differentiated Adipocytes

In obesity, there is an increase in reactive oxygen species (ROS) within adipose tissue caused by increases in inflammation and overnutrition. Hormone sensitive lipase (HSL) is part of the canonical lipolytic pathway and critical for complete lipolysis. This study hypothesizes that ROS is a signal t...

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Detalles Bibliográficos
Autores principales: Krawczyk, Sarah A., Haller, Jorge F., Ferrante, Tom, Zoeller, Raphael A., Corkey, Barbara E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321042/
https://www.ncbi.nlm.nih.gov/pubmed/22493722
http://dx.doi.org/10.1371/journal.pone.0034904