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Reactive Oxygen Species Facilitate Translocation of Hormone Sensitive Lipase to the Lipid Droplet During Lipolysis in Human Differentiated Adipocytes
In obesity, there is an increase in reactive oxygen species (ROS) within adipose tissue caused by increases in inflammation and overnutrition. Hormone sensitive lipase (HSL) is part of the canonical lipolytic pathway and critical for complete lipolysis. This study hypothesizes that ROS is a signal t...
Autores principales: | Krawczyk, Sarah A., Haller, Jorge F., Ferrante, Tom, Zoeller, Raphael A., Corkey, Barbara E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321042/ https://www.ncbi.nlm.nih.gov/pubmed/22493722 http://dx.doi.org/10.1371/journal.pone.0034904 |
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