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Wild type microglia arrest pathology in a mouse model of Rett syndrome
Rett syndrome is an X-linked autism spectrum disorder. The disease is characterized in the majority of cases by mutation of the MECP2 gene, which encodes a methyl-CpG-binding protein (1–5). Although MeCP2 is expressed in many tissues, the disease is generally attributed to a primary neuronal dysfunc...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321067/ https://www.ncbi.nlm.nih.gov/pubmed/22425995 http://dx.doi.org/10.1038/nature10907 |