MAP and Kinesin dependent nuclear positioning is required for skeletal muscle function

The basic unit of skeletal muscle in all metazoans is the multinucleate myofiber, within which individual nuclei are regularly positioned(1). The molecular machinery responsible for myonuclear positioning is not known. Improperly positioned nuclei are a hallmark of numerous muscles diseases(2), incl...

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Detalles Bibliográficos
Autores principales: Metzger, Thomas, Gache, Vincent, Xu, Mu, Cadot, Bruno, Folker, Eric S., Richardson, Brian E., Gomes, Edgar R., Baylies, Mary K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321085/
https://www.ncbi.nlm.nih.gov/pubmed/22425998
http://dx.doi.org/10.1038/nature10914

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321085/
https://www.ncbi.nlm.nih.gov/pubmed/22425998
http://dx.doi.org/10.1038/nature10914

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