Cargando…

ORC1 BAH domain links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome

Recognition of distinctly modified histones by specialized “effector” proteins constitutes a key mechanism for transducing molecular events at chromatin to biological outcomes(1). Effector proteins influence DNA-templated processes, including transcription, DNA recombination, and DNA repair; however...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuo, Alex J., Song, Jikui, Cheung, Peggie, Ishibe-Murakami, Satoko, Yamazoe, Sayumi, Chen, James K., Patel, Dinshaw J., Gozani, Or
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321094/
https://www.ncbi.nlm.nih.gov/pubmed/22398447
http://dx.doi.org/10.1038/nature10956