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ORC1 BAH domain links H4K20me2 to DNA replication licensing and Meier-Gorlin syndrome
Recognition of distinctly modified histones by specialized “effector” proteins constitutes a key mechanism for transducing molecular events at chromatin to biological outcomes(1). Effector proteins influence DNA-templated processes, including transcription, DNA recombination, and DNA repair; however...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321094/ https://www.ncbi.nlm.nih.gov/pubmed/22398447 http://dx.doi.org/10.1038/nature10956 |