IL-17A produced by αβ T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction

Emerging evidence suggests that the T(H)17 subset of αβ T cells contributes to the development of allergic asthma. In this study we found that mice lacking αvβ8 on dendritic cells failed to generate T(H)17 cells in the lung and were protected from AHR in response to house dust mite and ovalbumin sen...

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Detalles Bibliográficos
Autores principales: Kudo, Makoto, Melton, Andrew C., Chen, Chun, Engler, Mary B., Huang, Katherine E., Ren, Xin, Wang, Yanli, Bernstein, Xin, Li, John T., Atabai, Kamran, Huang, Xiaozhu, Sheppard, Dean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321096/
https://www.ncbi.nlm.nih.gov/pubmed/22388091
http://dx.doi.org/10.1038/nm.2684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321096/
https://www.ncbi.nlm.nih.gov/pubmed/22388091
http://dx.doi.org/10.1038/nm.2684

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