DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients

In addition to genetic predisposition, environmental and lifestyle factors contribute to the pathogenesis of type 2 diabetes (T2D). Epigenetic changes may provide the link for translating environmental exposures into pathological mechanisms. In this study, we performed the first comprehensive DNA me...

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Detalles Bibliográficos
Autores principales: Volkmar, Michael, Dedeurwaerder, Sarah, Cunha, Daniel A, Ndlovu, Matladi N, Defrance, Matthieu, Deplus, Rachel, Calonne, Emilie, Volkmar, Ute, Igoillo-Esteve, Mariana, Naamane, Najib, Del Guerra, Silvia, Masini, Matilde, Bugliani, Marco, Marchetti, Piero, Cnop, Miriam, Eizirik, Decio L, Fuks, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321176/
https://www.ncbi.nlm.nih.gov/pubmed/22293752
http://dx.doi.org/10.1038/emboj.2011.503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321176/
https://www.ncbi.nlm.nih.gov/pubmed/22293752
http://dx.doi.org/10.1038/emboj.2011.503

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