Coordination of multiple enzyme activities by a single PCNA in archaeal Okazaki fragment maturation

Chromosomal DNA replication requires one daughter strand—the lagging strand—to be synthesised as a series of discontinuous, RNA-primed Okazaki fragments, which must subsequently be matured into a single covalent DNA strand. Here, we describe the reconstitution of Okazaki fragment maturation in vitro...

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Detalles Bibliográficos
Autores principales: Beattie, Thomas R, Bell, Stephen D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321178/
https://www.ncbi.nlm.nih.gov/pubmed/22307085
http://dx.doi.org/10.1038/emboj.2012.12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321178/
https://www.ncbi.nlm.nih.gov/pubmed/22307085
http://dx.doi.org/10.1038/emboj.2012.12

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