Insights into Chi recognition from the structure of an AddAB-type helicase–nuclease complex

In bacterial cells, processing of double-stranded DNA breaks for repair by homologous recombination is dependent upon the recombination hotspot sequence Chi and is catalysed by either an AddAB- or RecBCD-type helicase–nuclease. Here, we report the crystal structure of AddAB bound to DNA. The structu...

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Detalles Bibliográficos
Autores principales: Saikrishnan, Kayarat, Yeeles, Joseph T, Gilhooly, Neville S, Krajewski, Wojciech W, Dillingham, Mark S, Wigley, Dale B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321194/
https://www.ncbi.nlm.nih.gov/pubmed/22307084
http://dx.doi.org/10.1038/emboj.2012.9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321194/
https://www.ncbi.nlm.nih.gov/pubmed/22307084
http://dx.doi.org/10.1038/emboj.2012.9

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