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Dissecting the role of glutathione biosynthesis in Plasmodium falciparum

Glutathione (γ-glutamylcysteinyl-glycine, GSH) has vital functions as thiol redox buffer and cofactor of antioxidant and detoxification enzymes. Plasmodium falciparum possesses a functional GSH biosynthesis pathway and contains mM concentrations of the tripeptide. It was impossible to delete in P. f...

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Detalles Bibliográficos
Autores principales: Patzewitz, Eva-Maria, Wong, Eleanor H, Müller, Sylke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321222/
https://www.ncbi.nlm.nih.gov/pubmed/22151036
http://dx.doi.org/10.1111/j.1365-2958.2011.07933.x