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Paraoxonase Activity and Expression Is Modulated by Therapeutics in Experimental Rat Nonalcoholic Fatty Liver Disease

Objective. The objective of the present study is to investigate the effect of rosiglitazone, metformin, ezetimibe, and valsartan (alone or in combinations) on paraoxonase (PON) activity and PON-mRNA expression in nonalcoholic fatty liver disease (NAFLD). Methods. 54 Male Sprague–Dawley rats were div...

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Detalles Bibliográficos
Autores principales: Hussein, O., Zidan, J., Abu Jabal, K., Shams, I., Szvalb, S., Grozovski, M., Bersudsky, I., Karry, R., Aviram, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321281/
https://www.ncbi.nlm.nih.gov/pubmed/22536512
http://dx.doi.org/10.1155/2012/265305