Present and Future of EGFR Inhibitors for Head and Neck Squamous Cell Cancer

Although EGFR is expressed at high levels in head and neck squamous cell carcinomas (HNSCCs) and mutations are extremely rare, monotherapy with EGFR inhibitors has shown limited success. The PI3kinase/Akt pathway is responsible for cellular survival, and inhibition of phosphatidylinositol (PI) synth...

Descripción completa

Detalles Bibliográficos
Autores principales: Baba, Yuh, Fujii, Masato, Tokumaru, Yutaka, Kato, Yasumasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321461/
https://www.ncbi.nlm.nih.gov/pubmed/22545054
http://dx.doi.org/10.1155/2012/986725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321461/
https://www.ncbi.nlm.nih.gov/pubmed/22545054
http://dx.doi.org/10.1155/2012/986725

Ejemplares similares