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Modulation of Telomeres in Alternative Lengthening of Telomeres Type I Like Human Cells by the Expression of Werner Protein and Telomerase

The alternative lengthening of telomeres (ALT) is a recombination-based mechanism of telomere maintenance activated in 5–20% of human cancers. In Saccharomyces cerevisiae, survivors that arise after inactivation of telomerase can be classified as type I or type II ALT. In type I, telomeres have a ta...

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Detalles Bibliográficos
Autores principales: Siddiqa, Aisha, Cavazos, David, Chavez, Jeffery, Long, Linda, Marciniak, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321466/
https://www.ncbi.nlm.nih.gov/pubmed/22545052
http://dx.doi.org/10.1155/2012/806382