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Ethanol Activation of Protein Kinase A Regulates GABA(A) Receptor Subunit Expression in the Cerebral Cortex and Contributes to Ethanol-Induced Hypnosis

Protein kinases are implicated in neuronal cell functions such as modulation of ion channel function, trafficking, and synaptic excitability. Both protein kinase C (PKC) and A (PKA) are involved in regulation of γ-aminobutyric acid type A (GABA(A)) receptors through phosphorylation. However, the rol...

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Detalles Bibliográficos
Autores principales: Kumar, Sandeep, Ren, Qinglu, Beckley, Jonathon H., O’Buckley, Todd K., Gigante, Eduardo D., Santerre, Jessica L., Werner, David F., Morrow, A. Leslie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321501/
https://www.ncbi.nlm.nih.gov/pubmed/22509146
http://dx.doi.org/10.3389/fnins.2012.00044