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Cause or Effect: Misregulation of microRNA Pathways in Neurodegeneration

During normal aging or neurodegenerative diseases, neuronal survival and function depend on protein homeostasis, which is regulated by multiple mechanisms, including the microRNA (miRNA) pathway. In different cells types, the absence of Dicer, a key miRNA processing enzyme, leads to neurodegeneratio...

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Detalles Bibliográficos
Autores principales: Gascon, Eduardo, Gao, Fen-Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321503/
https://www.ncbi.nlm.nih.gov/pubmed/22509148
http://dx.doi.org/10.3389/fnins.2012.00048