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Evaluation of Hepatic Mitochondria and Hematological Parameters in Zidovudine-Treated B6C3F(1) Mice

The effects of 12-week exposure to zidovudine (AZT) at 400, 500, and 600 mg/kg/d were examined on expression of 542 mitochondria-related genes and mitochondrial DNA (mtDNA) copy number in the liver of male and female B6C3F(1) mice to understand mitochondrial role in sex-related differences in develo...

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Detalles Bibliográficos
Autores principales: Desai, Varsha G., Lee, Taewon, Moland, Carrie L., Branham, William S., Mittelstaedt, Roberta A., Lewis, Sherry M., Leakey, Julian E. A., Fuscoe, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321529/
https://www.ncbi.nlm.nih.gov/pubmed/22545210
http://dx.doi.org/10.1155/2012/317695