Crosstalk between p53 and TGF-β Signalling

Wild-type p53 and TGF-β are key tumour suppressors which regulate an array of cellular responses. TGF-β signals in part via the Smad signal transduction pathway. Wild-type p53 and Smads physically interact and coordinately induce transcription of a number of key tumour suppressive genes. Conversely...

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Detalles Bibliográficos
Autores principales: Elston, Rebecca, Inman, Gareth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321553/
https://www.ncbi.nlm.nih.gov/pubmed/22545213
http://dx.doi.org/10.1155/2012/294097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321553/
https://www.ncbi.nlm.nih.gov/pubmed/22545213
http://dx.doi.org/10.1155/2012/294097

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