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In Vivo Clearance of Alpha-1 Acid Glycoprotein Is Influenced by the Extent of Its N-Linked Glycosylation and by Its Interaction with the Vessel Wall

Alpha-1 acid glycoprotein (AGP) is a highly glycosylated plasma protein that exerts vasoprotective effects. We hypothesized that AGP's N-linked glycans govern its rate of clearance from the circulation, and followed the disappearance of different forms of radiolabeled human AGP from the plasma...

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Detalles Bibliográficos
Autores principales: McCurdy, Teresa R., Bhakta, Varsha, Eltringham-Smith, Louise J., Gataiance, Sharon, Fox-Robichaud, Alison E., Sheffield, William P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321579/
https://www.ncbi.nlm.nih.gov/pubmed/22545002
http://dx.doi.org/10.1155/2012/292730