Retroviral Integrations in Gene Therapy Trials

γ-Retroviral and lentiviral vectors allow the permanent integration of a therapeutic transgene in target cells and have provided in the last decade a delivery platform for several successful gene therapy (GT) clinical approaches. However, the occurrence of adverse events due to insertional mutagenes...

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Detalles Bibliográficos
Autores principales: Biasco, Luca, Baricordi, Cristina, Aiuti, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321603/
https://www.ncbi.nlm.nih.gov/pubmed/22252453
http://dx.doi.org/10.1038/mt.2011.289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321603/
https://www.ncbi.nlm.nih.gov/pubmed/22252453
http://dx.doi.org/10.1038/mt.2011.289

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