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PKD is a kinase of Vps34 that mediates ROS-induced autophagy downstream of DAPk

Autophagy, a process in which cellular components are engulfed and degraded within double-membrane vesicles termed autophagosomes, has an important role in the response to oxidative damage. Here we identify a novel cascade of phosphorylation events, involving a network of protein and lipid kinases,...

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Detalles Bibliográficos
Autores principales: Eisenberg-Lerner, A, Kimchi, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321617/
https://www.ncbi.nlm.nih.gov/pubmed/22095288
http://dx.doi.org/10.1038/cdd.2011.149