Therapeutic targeting of Chk1 in NSCLC stem cells during chemotherapy

Cancer stem cell (SC) chemoresistance may be responsible for the poor clinical outcome of non-small-cell lung cancer (NSCLC) patients. In order to identify the molecular events that contribute to NSCLC chemoresistance, we investigated the DNA damage response in SCs derived from NSCLC patients. We fo...

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Detalles Bibliográficos
Autores principales: Bartucci, M, Svensson, S, Romania, P, Dattilo, R, Patrizii, M, Signore, M, Navarra, S, Lotti, F, Biffoni, M, Pilozzi, E, Duranti, E, Martinelli, S, Rinaldo, C, Zeuner, A, Maugeri-Saccà, M, Eramo, A, De Maria, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321626/
https://www.ncbi.nlm.nih.gov/pubmed/22117197
http://dx.doi.org/10.1038/cdd.2011.170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321626/
https://www.ncbi.nlm.nih.gov/pubmed/22117197
http://dx.doi.org/10.1038/cdd.2011.170

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