PRC1 and PRC2 Are Not Required for Targeting of H2A.Z to Developmental Genes in Embryonic Stem Cells

The essential histone variant H2A.Z localises to both active and silent chromatin sites. In embryonic stem cells (ESCs), H2A.Z is also reported to co-localise with polycomb repressive complex 2 (PRC2) at developmentally silenced genes. The mechanism of H2A.Z targeting is not clear, but a role for th...

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Detalles Bibliográficos
Autores principales: Illingworth, Robert S., Botting, Catherine H., Grimes, Graeme R., Bickmore, Wendy A., Eskeland, Ragnhild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322156/
https://www.ncbi.nlm.nih.gov/pubmed/22496869
http://dx.doi.org/10.1371/journal.pone.0034848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322156/
https://www.ncbi.nlm.nih.gov/pubmed/22496869
http://dx.doi.org/10.1371/journal.pone.0034848

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