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Chronic Infection Drives Expression of the Inhibitory Receptor CD200R, and Its Ligand CD200, by Mouse and Human CD4 T Cells

Certain parasites have evolved to evade the immune response and establish chronic infections that may persist for many years. T cell responses in these conditions become muted despite ongoing infection. Upregulation of surface receptors with inhibitory properties provides an immune cell-intrinsic me...

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Detalles Bibliográficos
Autores principales: Caserta, Stefano, Nausch, Norman, Sawtell, Amy, Drummond, Rebecca, Barr, Tom, MacDonald, Andrew S., Mutapi, Francisca, Zamoyska, Rose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322173/
https://www.ncbi.nlm.nih.gov/pubmed/22496920
http://dx.doi.org/10.1371/journal.pone.0035466