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Reversal of type 1 diabetes via islet β cell regeneration following immune modulation by cord blood-derived multipotent stem cells

BACKGROUND: Inability to control autoimmunity is the primary barrier to developing a cure for type 1 diabetes (T1D). Evidence that human cord blood-derived multipotent stem cells (CB-SCs) can control autoimmune responses by altering regulatory T cells (Tregs) and human islet β cell-specific T cell c...

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Detalles Bibliográficos
Autores principales: Zhao, Yong, Jiang, Zhaoshun, Zhao, Tingbao, Ye, Mingliang, Hu, Chengjin, Yin, Zhaohui, Li, Heng, Zhang, Ye, Diao, Yalin, Li, Yunxiang, Chen, Yingjian, Sun, Xiaoming, Fisk, Mary Beth, Skidgel, Randal, Holterman, Mark, Prabhakar, Bellur, Mazzone, Theodore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322343/
https://www.ncbi.nlm.nih.gov/pubmed/22233865
http://dx.doi.org/10.1186/1741-7015-10-3