Gene fragmentation in bacterial draft genomes: extent, consequences and mitigation

BACKGROUND: Ongoing technological advances in genome sequencing are allowing bacterial genomes to be sequenced at ever-lower cost. However, nearly all of these new techniques concomitantly decrease genome quality, primarily due to the inability of their relatively short read lengths to bridge certai...

Descripción completa

Detalles Bibliográficos
Autores principales: Klassen, Jonathan L, Currie, Cameron R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322347/
https://www.ncbi.nlm.nih.gov/pubmed/22233127
http://dx.doi.org/10.1186/1471-2164-13-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322347/
https://www.ncbi.nlm.nih.gov/pubmed/22233127
http://dx.doi.org/10.1186/1471-2164-13-14

Ejemplares similares