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Gene fragmentation in bacterial draft genomes: extent, consequences and mitigation
BACKGROUND: Ongoing technological advances in genome sequencing are allowing bacterial genomes to be sequenced at ever-lower cost. However, nearly all of these new techniques concomitantly decrease genome quality, primarily due to the inability of their relatively short read lengths to bridge certai...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322347/ https://www.ncbi.nlm.nih.gov/pubmed/22233127 http://dx.doi.org/10.1186/1471-2164-13-14 |