Plasmalogens Inhibit APP Processing by Directly Affecting γ-Secretase Activity in Alzheimer's Disease

Lipids play an important role as risk or protective factors in Alzheimer's disease (AD). Previously it has been shown that plasmalogens, the major brain phospholipids, are altered in AD. However, it remained unclear whether plasmalogens themselves are able to modulate amyloid precursor protein...

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Detalles Bibliográficos
Autores principales: Rothhaar, Tatjana L., Grösgen, Sven, Haupenthal, Viola J., Burg, Verena K., Hundsdörfer, Benjamin, Mett, Janine, Riemenschneider, Matthias, Grimm, Heike S., Hartmann, Tobias, Grimm, Marcus O. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific World Journal 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322458/
https://www.ncbi.nlm.nih.gov/pubmed/22547976
http://dx.doi.org/10.1100/2012/141240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322458/
https://www.ncbi.nlm.nih.gov/pubmed/22547976
http://dx.doi.org/10.1100/2012/141240

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